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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLNA All Species: 26.67
Human Site: S2158 Identified Species: 83.81
UniProt: P21333 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21333 NP_001104026.1 2647 280739 S2158 P S V A N V G S H C D L S L K
Chimpanzee Pan troglodytes XP_001173963 2623 280682 S2134 P S V A T V G S I C D L N L K
Rhesus Macaque Macaca mulatta XP_001091073 2647 280579 S2158 P S V A N V G S H C D L S L K
Dog Lupus familis XP_538205 2638 279885 S2150 P S V A N V G S H C N L S L K
Cat Felis silvestris
Mouse Mus musculus Q8BTM8 2647 281175 S2158 P S V A N I G S H C D L S L K
Rat Rattus norvegicus NP_001128071 2639 280476 S2150 P S V A N V G S H C D L S L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508334 2693 287074 S2204 P S V A N V G S H C D L S L K
Chicken Gallus gallus NP_989905 2610 272931 V2123 P E P T A H D V T A Q V T A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.4 99.2 97.6 N.A. 97.3 97 N.A. 87.6 74.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 82.2 99.6 98.3 N.A. 98.4 98.1 N.A. 93.5 85.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 100 93.3 N.A. 93.3 100 N.A. 100 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 100 100 N.A. 100 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 88 13 0 0 0 0 13 0 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 88 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 13 0 0 0 75 0 0 0 0 % D
% Glu: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 75 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 0 0 13 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 88 0 88 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 75 0 0 0 0 0 13 0 13 0 0 % N
% Pro: 100 0 13 0 0 0 0 0 0 0 0 0 0 0 13 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 88 0 0 0 0 0 88 0 0 0 0 75 0 0 % S
% Thr: 0 0 0 13 13 0 0 0 13 0 0 0 13 0 0 % T
% Val: 0 0 88 0 0 75 0 13 0 0 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _